This nematode is widespread throughout humid and tropical zones of asia, africa, the americas and the pacific islands, and is common in areas with poor socioeconomic levels1,2,7. Bite from an infected mosquito introduces third stage infective filarial larvae onto the human skin they penetrate into the bite wound to reach the lymphatics where they reside and develop into adults. Final host is man, harboring the adult worms, while the intermediate host is bloodsucking mosquito. Ppt wuchereria bancrofti powerpoint presentation free. Wuchereria bancrofti is a dreadful endoparasite of man.
Author summary infection with lymphatic filarial parasites usually occurs early in childhood in endemic areas, but clinical signs appear much later. Jun 20, 2017 wuchereria bancrofti filariasis for m. Bancrofti was named after physician otto wucherer and parasitologist joseph bancroft. The major vector in india and most other parts of asia is culex fatigans. The intermediate host is the female mosquito of the genus culex. More detailed information about the symptoms, causes, and treatments of wuchereria bancrofti is available below symptoms of wuchereria bancrofti.
Brugia malayi can be transmitted by the mosquito genera aedes, anopheles or mansonia, depending on the location and animal reservoirs present. Video explaining the parasitic life cycle of lymphatic filariasis in humans. Knowledge life cycle, pathogenicity and prophylaxis of. Cdc lymphatic filariasis life cycle of wuchereria bancrofti. While the peripheral blood smear and involved organs are characterized by intense eosinophilia, the histology of the lymph node may not reveal eosinophilic infiltration. Dec 03, 2018 the adult wuchereria bancrofti worms are white and threadlike. Wuchereria bancrofti is the infectious agent in 91 % of lf cases. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. Man is the only definitive host and no animal host or reservoir is known for w. These worms occupy the lymphatic system, including the lymph nodes.
Also known as the filarial worm as it causes a disease called as filariasis. What is the life cycle of the wuchereria bancrofti and brugia malayi. Different species of the following genera of mosquitoes are vectors of w. From the article, preventing two diseases with one net.
Scribd is the worlds largest social reading and publishing site. Salomon slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. It is a filarial roundworm parasite that lives in some species of mosquitoes and transmits the infection to man when the infected. Lymphatic filariasis elephantiasis life cycle impala nihr. To determine the extent of lymphatic disease in persons infected with wuchereria bancrofti who were microfilaraemic, we examined the superficial lymphatics of the legs by scintigraphy. Evaluation of wuchereria bancrofti gst as a vaccine candidate for lymphatic filariasis. Wuchereria bancrofti wb is the primary causative agent of lymphatic filariasis lf. Genus wuchereria species bancrofti wuchereria bancrofti is a nematode endoparasite inhabiting the lymphatic vessels andlymphat.
Our studies of lf in papua new guinea png have shown that it is possible to reduce the prevalence of wb in. Reversal of lymphatic pathology has been shown with the much less common brugia malayi infection using dec and albendazole and there is scarce evidence whether the same occurs with bancroftian filariasis using the above drugs. The nematode parasite wuchereria bancrofti is responsible for 90% of this global disease burden. Skip directly to site content skip directly to page options skip directly to az link. Male and female worms copulate when they are present in the same lymph gland. Wuchereria bancrofti, are important causes of diseases in humans. Bancroftian filariasis isan ancient disease known to man kind since be 600. If you continue browsing the site, you agree to the use of cookies on this website. The life cycle of lymphatic filariasis carter center. Nov 30, 2016 this article will explore lymphatic filariasis. Filariasis due to wuchereria bancrofti has a worldwide spread in tro pical and subtropical areas of africa, asia, pacific islands, central and south america, and the caribbean wilso n, 1991. Lymphatic filariasis lf is a disabling, disfiguring, and poverty promoting disease that affects an estimated 120 million individuals in developing countries. The adult worm inhabits the lymphatics and the female produces sheathed microfilariae which circulate in the peripheral. Evaluation of wuchereria bancrofti gst as a vaccine.
Evaluation of wuchereria bancrofti gst as a vaccine candidate. Pcr screening of the cdna libraries of different life cycle stages of w. Wuchereria bancrofti lymphatic filariasis elephantiasis. These filarial worms are spread by a variety of mosquito vector species. Sequence and timing of life cycle stages within a host importance in treatment control optimal time for diagnosis application of life cycle knowledge mf of wuchereria bancrofti exhibits periodicity. Life cycle of wuchereria bancrofti, a parasite that causes filariasis. Ancient greek and roman writers noted the similarities between the. I nfection with three closely related filarial worms wuchereria bancrofti, brugia malayi and brugia timorieach causative agents of what is termed lymphatic filariasis lf, are vector mosquitoborne infections with similar life cycles that involve the adult worms living in the afferent lymphatics andor the lymph nodes while their larval progeny, the microfilariae. National center for infectious disease, divison of parasitic diseases.
Lymphatic filariasis references stanford university. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. The females are usually larger than the males, 40 to 100 mm and 20 to 40 mm respectively. There are about five more common, including wuchereria bancrofti and brugia malayi, and four less common filarial parasites infecting human. Filaria are frequently found in the enlarged lymph node. Education and information about lymphatic filariasis biology, specifically the life cycle of wuchereria bancrofti.
Following mating the female worm lays eggs which hatches to give rise to larvae or juveniles called microfilariae. Wuchereria is a heterogeneous parasite which completes its life cycle in two different hosts namely man and female culex mosquito. In 4 endemic control subjects and in 10 of 14 clinically asymptomatic microfilaraemic individuals, lymphoscintigraphy revealed one major channel of lymphatic drainage in each leg. Lymphatic filariasis consortium of universities for global. It is one of the three parasitic worms, together with brugia malayi and b. All structured data from the file and property namespaces is available under the creative commons cc0 license. Life cycle, pathogenicity and prophylaxis of wuchereria. Like malarial parasite the life cycle of filaria bancrofti is digenetic involving two hosts. Lymphatic pathology in asymptomatic and symptomatic children. Lymphatic filariasis is a parasitic disease caused by threadlike worms called wuchereria bancrofti. Lymphatic filariasis introduction stanford university. Wuchereria bancrofti life cycle, morphology, mode of transmission, daignosis and prevention of infection. Keywords lymphatic filariasis, parasite, life cycle. Wuchereria bancrofti symptoms, diagnosis, treatments and.
Wuchereria bancrofti is a dreaded human endoparasite of human blood and lymph. The process of copulation takes place in the lymphatic system of the human. Occult filariasis pdf occult filariasis in crows corvus brachyrhynchos brachyrhynchos. Ppt filariasis powerpoint presentation free to download. The first stage larvae or microfilariae are released from fecund adult female worms that release up to 10,000 microfilariae per day, which circulate in the blood. It is a digenetic parasite completing its life cycle in two hosts. The best sleeping position for back pain, neck pain, and sciatica tips from a physical therapist duration.
Ppt lymphatic filariasis powerpoint presentation free to. Brugian filariasis also does not characteristically include symptoms associated with. The thirdstage infective nematode larvae l3i enter the blood through the wound made by the mosquito. Winner of the standing ovation award for best powerpoint templates from presentations magazine. The causative agents of lymphatic filariasis lf include the mosquitoborne filarial nematodes wuchereria bancrofti, brugia malayi, b. Wuchereria bancroftiand brugia malayi, and four less common. Wuchereria bancrofti life cycle, morphology, mode of. Files are available under licenses specified on their description page. Lymphatic filariasis lf is transmitted by mosquitoes, so risk factors include those that are conducive to the life cycle of mosquitoes poor drainage, vector breeding sites poor sanitation vulnerability to mosquito bites due to low insecticidetreated net itn use, etc. The parasite is carried from person to person by mosquitoes. Lymphatic filariasis elephantiasis life cycle youtube. Displaying powerpoint presentation on wuchereria bancrofti available to view or download.
Jan 27, 2017 video explaining the parasitic life cycle of lymphatic filariasis in humans. Subcutaneous filariasis is caused by loa loa the eye worm, mansonella streptocerca, and onchocerca volvulus. In this article we will discuss about wucheria bancrofti. Wuchereria bancrofti is distributed throughout the tropical regions of asia, africa, china, the pacific and isolated locations in the americas. Author summary lymphatic filariasis is a disabling and disfiguring disease caused by a parasite that is transmitted by a mosquito. Distributed throughout the tropical regions of asia, africa, china, the pacific and isolated locations in the americas. The anopheles mosquito can also transmit wuchereria bancrofti, so that coinfection can be theoretically possible. Wuchereria bancrofti introduction wuchereria bancrofti is a nematode causing lymphatic filariasis throughout the tropics and subtropics. All other aspects of brugia malayi s life cycle are similar to that of wuchereria. Fertilized female worms release embryonic offspring, called microfilariae, that enter the blood stream. Filariasis wuchereria bancrofti linkedin slideshare. Detection of wuchereria bancrofti l3 larvae in mosquitoes. Insights into the pathogenesis of disease in human. Global programme to eliminate lymphatic filariasis understanding of filarial transmission and vectors.
Man is the definitive host and the adult worms and the live embryos microfilariae inhabit in the lymphatic system and blood stream. Current estimates who, 1994 suggest that 100 million people are infected with lymphatic filariae of all types, and most of these cases are bancroftian filariasis. Distribution, life cycle, mode of transmission and treatment. Wuchereria bancrofti requires two hosts for completion of its life cycle. Dec 27, 2018 brugia malayi can be transmitted by the mosquito genera aedes, anopheles or mansonia, depending on the location and animal reservoirs present. The culex, aedes and anopheles spp of mosquitoes serve as wuchereria bancrofti. A mosquito vector can bite the infected human host, ingest the microfilariae, and thus repeat the lifecycle. The life cycle of lymphatic filariasis swelling an infected mosquito deposits larvae on the skin while biting, and the larvae enter the wound. Wuchereria bancrofti infected population, the major contributor to lf globally. In 4 endemic control subjects and in 10 of 14 clinically asymptomatic microfilaraemic individuals, lymphoscintigraphy revealed one major channel of lymphatic.
The adult filarial parasites are tissue specific in the human host and their embryonic stage, called microfilariae mf, are found in. Phylum nemathelminthes class nematoda advertisements. Ancient greek and roman writers noted the similarities between the enlarged limbs and cracked skin of. Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience. Wuchereria bancrofti it is a human parasitic roundworm that is the major cause of lymphatic filariasis. The document will also be useful for teaching personnel in lymphatic filariasis programmes about the use and value of entomological procedures in overall epidemiological appraisal in the context of elimination. Wuchereria bancrofti an overview sciencedirect topics. Wuchereria bancrofti is a human parasitic worm filariworm that is the major cause of lymphatic filariasis.
It is more common to find elephantiasis in patients affected with w. Sc students slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Occult filariasis pdf occult filariasis pdf download. Lymphatic pathology in wuchereria bancrofti microfilaraemic. Wuchereria bancrofti are filarial worms are long, thin tapering worms without lips around mouth. Lf is also recognized as the second most disabling mosquitoborne disease next to malaria1,4,5,6. This page was last edited on 11 january 2019, at 08. The culex, aedes and anopheles spp of mosquitoes serve as wuchereria bancrofti s intermediary hosts and vectors. The adult wuchereria bancrofti worms are white and threadlike. Wuchereria bancrofti and brugia malayi flashcards quizlet. Lymphadenopathy is the striking feature of infection with wuchereria bancrofti. Adults live in lymphatics release microfilariae into lymph mf circulate in blood mf ingested by mosquitoes during blood meal mf develop into infective stage in mosquito mosquito transmits infective larvae during blood meal. The life cycle, in common with all nematodes, has five developmental or larval stages in a vertebral host and an arthropod intermediate host and vector. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from.